Vancomycine 500 Mg

• Vancomycin Hydrochloride Injection 500 mg  is a tricyclic glycopeptides antibiotic derived from Amycolatopsis orientalis. Vancomycin is indicated for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci. It is indicated for penicillin-allergic patients, for patients who cannot receive or who have failed to respond to other drugs, including the penicillin’s or cephalosporins .
• Vancoshot is indicated for initial therapy when methicillin resistant staphylococci are suspected, but after susceptibility data are available, therapy should be adjusted accordingly. Vancomycin is effective in the treatment of staphylococcal endocarditis. Its effectiveness has been documented in other infections due to staphylococci, including septicaemia, bone infections, lower respiratory tract infections, skin and skin structure infections. When staphylococcal infections are localized and purulent, antibiotics are used as adjuncts to appropriate surgical measures.

ADDITIONAL INFORMATION

• Rapid bolus administration (e.g. over several minutes) may be associated with exaggerated hypotension, including shock, and, rarely, cardiac arrest.
• Vancoshot should be administered over a period of not less than 60 minutes to avoid rapid-infusion-related reactions. Stopping the infusion usually results in prompt cessation of these reactions.

SIDE EFFECTS & INFUSION-RELATED EVENTS

• During or soon after rapid infusion of vancomycin, patients may develop anaphylactic reactions, including hypotension, wheezing, dyspnoea, urticaria. Rapid infusion may also cause flushing of the upper body

NEPHROTOXICITY

• Renal failure, principally manifested by increased serum creatinine or BUN concentrations, especially in patients administered large doses of vancomycin, has been reported rarely.

GASTROINTESTINAL

• Onset of pseudo membranous colitis symptoms may occur during or after antibiotic treatment .

Vancoshot ( Vancomycin 500/1 Gm Injection)